Muscle ultrasound as a tool for respiratory assessment in patients with LAMA2-MD

Background: LAMA2-muscular dystrophy (LAMA2-MD) is an autosomal recessive disease, and the most common form of congenital muscular (CMD). Most patients develop a disease characterized by inability to achieve walking capacity, multiple joint deformities, respiratory insufficiency, some degree dysphagia. However, there gravity spectrum, never sitting position, while others can walk unassisted. There are still no adequate biomarkers assess progression, muscle ultrasound be useful tool, also complement assessment swallowing function.